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  • DC Chemicals Limited
  • China
  • Product Name: Hexane-1
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  • Purity: 98.0%
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  • Contact: Tony Cao

4721-22-6

4721-22-6 structure
4721-22-6 structure
  • Name: Hexane-1,6-diyldiphosphonic acid
  • Chemical Name: 6-phosphonohexylphosphonic acid
  • CAS Number: 4721-22-6
  • Molecular Formula: C6H16O6P2
  • Molecular Weight: 246.13500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-01-03 04:32:21
  • Modify Date: 2024-01-08 17:23:14
  • Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 6-phosphonohexylphosphonic acid
Synonyms 1,6-hexylenediphosphonic acid
1,6-HEXYLENEBISPHOSPHONIC ACID
hexane-1,6-diylbisphosphonic acid
hexane-1,6-diyldiphosphonic acid
1,6-Hexanebisphosphonic acid
1,6-Diphosphono-hexan
1,6-hexanediphosphonic acid
hexane-1,6-bisphosphonic acid
Description Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Melting Point 206 °C
Molecular Formula C6H16O6P2
Molecular Weight 246.13500
Exact Mass 246.04200
PSA 134.68000
LogP 0.90220
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P280-P305 + P351 + P338-P337 + P313
Hazard Codes C
RIDADR NONH for all modes of transport
Precursor  3

DownStream  0