809234-33-1
809234-33-1 structure
- Name: 4-(Chloromethyl)-5,7-dihydroxy-2H-chroMen-2-one
- Chemical Name: 4-(chloromethyl)-5,7-dihydroxychromen-2-one
- CAS Number: 809234-33-1
- Molecular Formula: C10H7ClO4
- Molecular Weight: 226.61
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2016-11-20 08:56:09
- Modify Date: 2024-01-09 18:54:19
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DNA polymerase-IN-1 (compound 2d) is a DNA polymerase inhibitor (IC50=20.7 μM) with antiproliferative activity against tumor cells[1].
| Name | 4-(chloromethyl)-5,7-dihydroxychromen-2-one |
|---|---|
| Synonyms |
2H-1-Benzopyran-2-one,4-(chloromethyl)-5,7-dihydroxy
4-(chloromethyl)-5,7-dihydroxy-2H-chromen-2-one 4-chloromethyl-5,7-dihydroxycoumarin 4-(chloromethyl)-5,7-dihydroxy-2H-1-benzopyran-2-one 4-chloromethyl-5-hydroxyumbelliferone |
| Description | DNA polymerase-IN-1 (compound 2d) is a DNA polymerase inhibitor (IC50=20.7 μM) with antiproliferative activity against tumor cells[1]. |
|---|---|
| Related Catalog | |
| Target |
DNA polymerase[1] |
| In Vivo | DNA polymerase-IN-1 (compound 2d) |
| References |
| Molecular Formula | C10H7ClO4 |
|---|---|
| Molecular Weight | 226.61 |
| Exact Mass | 226.00300 |
| PSA | 70.67000 |
| LogP | 1.94300 |
| HS Code | 2932209090 |
|---|
|
~96%
809234-33-1 |
| Literature: Karami, Bahador; Kiani, Mahtab Journal of the Chinese Chemical Society, 2014 , vol. 61, # 2 p. 213 - 216 |
|
~94%
809234-33-1 |
| Literature: Sharghi, Hashem; Jokar, Mahboubeh Heterocycles, 2007 , vol. 71, # 12 p. 2721 - 2733 |
|
~%
809234-33-1 |
| Literature: Karami, Bahador; Khodabakhshi, Saeed; Eskandari, Khalil Chemical Papers, 2013 , vol. 67, # 11 p. 1474 - 1478 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |