CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UK8021500
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CHEMICAL NAME :
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Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, methyl ester, (5Z,9-alpha,11-alpha, 13E,15S)-
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CAS REGISTRY NUMBER :
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33854-16-9
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C21-H36-O5
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MOLECULAR WEIGHT :
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368.57
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravaginal
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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80 ug/kg
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TOXIC EFFECTS :
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Gastrointestinal - nausea or vomiting
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REFERENCE :
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JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 102,620,1983 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravaginal
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DOSE :
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80 ug/kg
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SEX/DURATION :
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female 7 week(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system
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REFERENCE :
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JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 102,620,1983
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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480 ug/kg
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SEX/DURATION :
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female 4 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 186,67,1973
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