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20243-59-8

20243-59-8 structure
20243-59-8 structure
  • Name: Hydroxygenkwanin
  • Chemical Name: hydroxygenkwanin
  • CAS Number: 20243-59-8
  • Molecular Formula: C16H12O6
  • Molecular Weight: 300.263
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-05-09 08:00:00
  • Modify Date: 2024-01-05 12:10:20
  • Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].

Name hydroxygenkwanin
Synonyms 3',4',5-Trihydroxy-7-methoxyflavone
5,3',4'-trihydroxy-7-methoxyflavanone
7-O-Methylluteolin
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-
luteolin 7-methyl ester
3',4',5-trihydroxy-7-methoxyflavanone
5,3',4'-Trihydroxy-7-methoxyflavone
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one
Luteolin 7-methyl ether
luteolin-7-methylether
Description Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].
Related Catalog
In Vitro Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2].
References

[1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55.

[2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911.

Density 1.5±0.1 g/cm3
Boiling Point 602.7±55.0 °C at 760 mmHg
Melting Point 225-227ºC
Molecular Formula C16H12O6
Molecular Weight 300.263
Flash Point 230.6±25.0 °C
Exact Mass 300.063385
PSA 100.13000
LogP 2.65
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.697
HS Code 2932999099

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20243-59-8

Literature: Ellemose, Steen; Kure, Niels; Torsell, Kurt B. G. Acta Chemica Scandinavica, 1995 , vol. 49, # 7 p. 524 - 529

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20243-59-8 structure

20243-59-8

Literature: Pankajamani; Seshadri Journal of the Indian Chemical Society, 1954 , vol. 31, p. 565

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Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

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20243-59-8 structure

20243-59-8

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%