Hydroxygenkwanin

Modify Date: 2024-01-05 12:10:20

Hydroxygenkwanin Structure
Hydroxygenkwanin structure
Common Name Hydroxygenkwanin
CAS Number 20243-59-8 Molecular Weight 300.263
Density 1.5±0.1 g/cm3 Boiling Point 602.7±55.0 °C at 760 mmHg
Molecular Formula C16H12O6 Melting Point 225-227ºC
MSDS N/A Flash Point 230.6±25.0 °C

 Use of Hydroxygenkwanin


Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].

 Names

Name hydroxygenkwanin
Synonym More Synonyms

 Hydroxygenkwanin Biological Activity

Description Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].
Related Catalog
In Vitro Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2].
References

[1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55.

[2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 602.7±55.0 °C at 760 mmHg
Melting Point 225-227ºC
Molecular Formula C16H12O6
Molecular Weight 300.263
Flash Point 230.6±25.0 °C
Exact Mass 300.063385
PSA 100.13000
LogP 2.65
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.697

 Safety Information

HS Code 2932999099

 Synthetic Route

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Hydroxygenkwanin Structure

Hydroxygenkwanin

CAS#:20243-59-8

Literature: Ellemose, Steen; Kure, Niels; Torsell, Kurt B. G. Acta Chemica Scandinavica, 1995 , vol. 49, # 7 p. 524 - 529

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Hydroxygenkwanin Structure

Hydroxygenkwanin

CAS#:20243-59-8

Literature: Pankajamani; Seshadri Journal of the Indian Chemical Society, 1954 , vol. 31, p. 565

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Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

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Hydroxygenkwanin Structure

Hydroxygenkwanin

CAS#:20243-59-8

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3',4',5-Trihydroxy-7-methoxyflavone
5,3',4'-trihydroxy-7-methoxyflavanone
7-O-Methylluteolin
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-
luteolin 7-methyl ester
3',4',5-trihydroxy-7-methoxyflavanone
5,3',4'-Trihydroxy-7-methoxyflavone
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one
Luteolin 7-methyl ether
luteolin-7-methylether
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