81189-92-6

81189-92-6 structure

Name: Acetyllovastatin
Chemical Name: acetyllovastatin
CAS Number: 81189-92-6
Molecular Formula: C₂₆H₃₈O₆
Molecular Weight: 446.57600
Catalog: Research Areas Infection
Create Date: 2017-08-30 07:50:10
Modify Date: 2024-01-09 17:16:59
Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].

Name	acetyllovastatin
Synonyms	4-acetyl lovastatin (2E)-1-[3-(Acetyloxy)-2,6,6-trimethyl-1-cyclohexen-1-yl]-2-buten-1-one 4-Acetoxy--damascone

Description	Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IC50: 79 μg/mL (The enzyme acetylcholinesterase)[1]
References	[1]. Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067–1075.

145576-24-5

29138-64-5

~1%

210980-68-0

850920-00-2

Detail

Literature: DIVERSA CORPORATION Patent: WO2005/40107 A2, 2005 ; Location in patent: Page/Page column 41-43; 80-82 ;