Name | [(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate |
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Synonyms |
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester
anhydrosimvastatin (1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-{2-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate Dehydrosimvastatin Dehydro Simvastatin Anhydro-simvastatin Simvastatin EP Impurity C Dehydrosimvastatin Simvastatin Impurity 3 |
Description | Anhydrosimvastatin (Impurity C) is an impurity of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase[1]. |
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Related Catalog | |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 536.8±50.0 °C at 760 mmHg |
Molecular Formula | C25H36O4 |
Molecular Weight | 400.551 |
Flash Point | 265.6±28.5 °C |
Exact Mass | 400.261353 |
PSA | 52.60000 |
LogP | 5.81 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.529 |
Hazard Codes | Xi |
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RIDADR | NONH for all modes of transport |
~4% 210980-68-0 |
Literature: WO2005/40107 A2, ; Page/Page column 31-32; 61-62 ; |
Detail
|
Literature: WO2005/40107 A2, ; Page/Page column 51-53 ; |
~% 210980-68-0 |
Literature: WO2005/40107 A2, ; Page/Page column 73-74 ; |
~12% 210980-68-0
Detail
|
Literature: WO2005/40107 A2, ; Page/Page column 45; 83 ; |
~0% 210980-68-0
Detail
|
Literature: WO2005/40107 A2, ; Page/Page column 41-43; 80-82 ; |
~% 210980-68-0 |
Literature: WO2005/40107 A2, ; Page/Page column 75-76 ; |
Precursor 6 | |
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DownStream 0 |