Name | prilocaine hydrochloride |
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Synonyms |
N-(α-Propylaminopropionyl)-o-toluidine hydrochloride
EINECS 217-244-0 PrilocaineHydrochloroide xylonest Prilocaine hydrochloride N-(2-Methylphenyl)-2-(propylamino)propanamidhydrochlorid propitocaine hydrochloride N-(2-Methylphenyl)-N-propylalaninamide hydrochloride 3MY1&VMR B1 &&HCl prilocainechloride l-67hydrochloride N-(2-Methylphenyl)-N-propylalaninamide hydrochloride (1:1) N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride MFCD00079279 Citanest Plain PRILOCAINE HCL Propanamide, N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1) Propitocaine HCL citanesthydrochloride N-(2-methylphenyl)-N2-propylalaninamide hydrochloride 2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride Prilocaine HC |
Description | Prilocaine hydrochloride is a local anesthetic of the amino amide type.Target: OthersPrilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils L?fgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg.Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention. |
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Related Catalog | |
References |
[2]. Juhlin L, et al. EMLA: a new topical anesthetic. Adv Dermatol. 1990;5:75-91; discussion 92. |
Boiling Point | 85°C 4mm |
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Melting Point | 168-170ºC |
Molecular Formula | C13H21ClN2O |
Molecular Weight | 256.772 |
Flash Point | 134.3ºC |
Exact Mass | 256.134247 |
PSA | 41.13000 |
LogP | 3.58750 |
Vapour Pressure | 2.05E-05mmHg at 25°C |
Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
RTECS | UG5775000 |
HS Code | 2924299090 |
HS Code | 2924299090 |
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Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |