- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Kudinoside H
- Price:
- Purity: 99.2%
- Stocking Period: 10 Day
- Contact: Yang
- BioBioPha
- China
- Product Name: Ziyuglycoside I
- Price: ￥Inquiry/5mg
- Purity: 97.0%
- Stocking Period: 10 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Kudinoside H
- Price: ￥988.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I)
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- DC Chemicals Limited
- China
- Product Name: 3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester(Kudinoside H:Ziyuglycoside I)
- Price: $650.0/100mg $1200.0/250mg $2300.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
35286-58-9
35286-58-9 structure
- Name: Kudinoside H
- Chemical Name: Ziyuglycoside I
- CAS Number: 35286-58-9
- Molecular Formula: C41H66O13
- Molecular Weight: 766.955
- Catalog: Natural product Moss
- Create Date: 2018-04-07 08:00:00
- Modify Date: 2024-01-02 17:57:29
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Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics[1].Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential drug candidate for treating triple-negative breast cancer (TNBC)[2].
| Name | Ziyuglycoside I |
|---|---|
| Synonyms |
3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester
Kudinoside H ziyu-glycoside 1-O-[(3β)-3-(α-L-Arabinopyranosyloxy)-19-hydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose ziyu-glycoside I ziyuglucoside I β-D-Glucopyranose, 1-O-[(3β)-3-(α-L-arabinopyranosyloxy)-19-hydroxy-28-oxours-12-en-28-yl]- Gouguside 7 Zigu-glucoside I |
| Description | Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics[1].Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential drug candidate for treating triple-negative breast cancer (TNBC)[2]. |
|---|---|
| Related Catalog | |
| In Vitro | Ziyuglycoside I (5-160 µM; 24 hours) reveals a marked anti-proliferation activity with an IC50 value of 13.96 µM in MDA-MB-231 cells[2]. Ziyuglycoside I (5-20 µM; 24 hours) induces MDA-MB-231 cell apoptosis by increasing the percentage of apoptotic cells from 2.43% to 44.76% at 20 µM[2]. Ziyuglycoside I (5-20 µM; 24 hours) induces the cleavage of caspas-8, caspase-9, and caspase-3, up-regulates the pro-apoptotic protein Bax, and down-regulates anti-apoptotic protein Bal-2, dose-dependently reduces the level of mito-cyto c expression[2]. Cell Viability Assay[1] Cell Line: MDA-MB-231 cells Concentration: 5 µM, 10 µM, 20 µM, 40 µM, 80 µM, and 160 µM Incubation Time: 24 hours Result: Showed cytotoxicity on MDA-MB-231 cells. Cell Cycle Analysis[1] Cell Line: MDA-MB-231 cells Concentration: 5 µM, 10 µM, and 20 µM Incubation Time: 24 hours Result: Induced G2/M phase arrest and apoptosis on MDA-MB-231 Cells Western Blot Analysis[1] Cell Line: MDA-MB-231 cells Concentration: 5 µM, 10 µM, and 20 µM Incubation Time: 24 hours Result: Induced apoptosis in MDA-MB-231 Cells through Intrinsic and Extrinsic Pathways. |
| References |
| Density | 1.35 |
|---|---|
| Boiling Point | 841.9±65.0 °C at 760 mmHg |
| Melting Point | 198-202ºC |
| Molecular Formula | C41H66O13 |
| Molecular Weight | 766.955 |
| Flash Point | 247.2±27.8 °C |
| Exact Mass | 766.450317 |
| PSA | 215.83000 |
| LogP | 6.59 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.610 |
| Storage condition | 2-8°C |