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57462-42-7

57462-42-7 structure
57462-42-7 structure
  • Name: [Nle11]-Substance P
  • Chemical Name: arg-pro-lys-pro-gln-gln-phe-phe-gly-leu-nle-nh2
  • CAS Number: 57462-42-7
  • Molecular Formula: C64H100N18O13
  • Molecular Weight: 1329.592
  • Catalog: Peptides
  • Create Date: 2019-01-09 11:33:28
  • Modify Date: 2024-01-07 12:53:04
  • [Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.

Name arg-pro-lys-pro-gln-gln-phe-phe-gly-leu-nle-nh2
Synonyms L-Norleucinamide, N-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
substance P,NleNH2(11)
N-(diaminomethylidene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-norleucinamide
Substance P,[Nle11]
[Nle11 ]-substance P
N-(Diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-norleucinamide
[Nle11]-Substance P
Description [Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.
Related Catalog
In Vitro Substance P and its analog, [Nle11]-Substance P have shown similar potency in tests. The spasmogenic activity of Substance P and [Nle11]-Substance P are preserved in the same potency order on stimulated guinea-pig ileum[1].
References

[1]. Chipkin RE, et al. In vitro activities of some synthetic substance P analogs. Arch Int Pharmacodyn Ther. 1979 Aug;240(2):193-202.

Density 1.4±0.1 g/cm3
Molecular Formula C64H100N18O13
Molecular Weight 1329.592
Exact Mass 1328.771729
PSA 516.63000
LogP -0.18
Index of Refraction 1.654
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport