Name | arg-pro-lys-pro-gln-gln-phe-phe-gly-leu-nle-nh2 |
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Synonyms |
L-Norleucinamide, N-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
substance P,NleNH2(11) N-(diaminomethylidene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-norleucinamide Substance P,[Nle11] [Nle11 ]-substance P N-(Diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-norleucinamide [Nle11]-Substance P |
Description | [Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems. |
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Related Catalog | |
In Vitro | Substance P and its analog, [Nle11]-Substance P have shown similar potency in tests. The spasmogenic activity of Substance P and [Nle11]-Substance P are preserved in the same potency order on stimulated guinea-pig ileum[1]. |
References |
Density | 1.4±0.1 g/cm3 |
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Molecular Formula | C64H100N18O13 |
Molecular Weight | 1329.592 |
Exact Mass | 1328.771729 |
PSA | 516.63000 |
LogP | -0.18 |
Index of Refraction | 1.654 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
~%
Detail
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Literature: Journal of Medicinal Chemistry, , vol. 25, # 1 p. 64 - 68 |
Precursor 4 | |
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DownStream 0 |