Name | 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
---|---|
Synonyms |
Nonaethylene Glycol Monomethyl Ether
O-methyl-nonaethyleneglycol O-Methyl-nonaaethylenglykol 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanol 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol O-methyl-nonaaethylene glycol Nonaethylene glycol monomethyl ether MPEG9-OH |
Description | Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 490.1±40.0 °C at 760 mmHg |
Melting Point | 14ºC |
Molecular Formula | C19H40O10 |
Molecular Weight | 428.515 |
Flash Point | 250.2±27.3 °C |
Exact Mass | 428.262146 |
PSA | 103.30000 |
LogP | -3.66 |
Vapour Pressure | 0.0±2.8 mmHg at 25°C |
Index of Refraction | 1.453 |
Storage condition | 2-8°C |
HS Code | 2909440000 |
---|
~99% 6048-68-6 |
Literature: SMITHKLINE BEECHAM CORPORATION Patent: WO2005/102976 A1, 2005 ; Location in patent: Page/Page column 10-11 ; |
~49% 6048-68-6 |
Literature: UNIVERSITA DEGLI STUDI DI SIENA Patent: WO2008/37604 A1, 2008 ; Location in patent: Page/Page column 19 ; |
~% 6048-68-6 |
Literature: US2798873 , ; |
~% 6048-68-6 |
Literature: US2858315 , ; |
~% 6048-68-6 |
Literature: US2798873 , ; |
~% 6048-68-6 |
Literature: US2858315 , ; |
Precursor 6 | |
---|---|
DownStream 0 |
HS Code | 2909499000 |
---|---|
Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |