1020719-98-5

1020719-98-5 structure

Name: Triclosan D3
Chemical Name: 5-chloro-2-(2,4-dichloro-3,5,6-trideuteriophenoxy)phenol
CAS Number: 1020719-98-5
Molecular Formula: C₁₂H₇Cl₃O₂
Molecular Weight: 289.54200
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-08-12 18:13:30
Modify Date: 2024-01-12 14:07:17
Triclosan D3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].

Name	5-chloro-2-(2,4-dichloro-3,5,6-trideuteriophenoxy)phenol
Synonyms	2'-Hydroxy-2,4,4'-trichlorodiphenyl-d3 Ether Gamophen-d3 5-Chloro-2-(2,4-dichloro-3,5,6-d3-phenoxy)phenol-d3 Irgasan DP 300-d3 2,4,4'-Trichloro-2'-hydroxydiphenyl-d3 Ether Triclosan-d3 Aquasept-d3

Description	Triclosan D3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Weatherly LM, et al. Triclosan exposure, transformation, and human health effects. J Toxicol Environ Health B Crit Rev. 2017;20(8):447-469. [3]. Ley C, et al. Triclosan and triclocarban exposure and thyroid function during pregnancy-A randomized intervention. Reprod Toxicol. 2017 Dec;74:143-149.