4105-38-8

4105-38-8 structure

Name: uridine triacetate
Chemical Name: 2',3',5'-Tri-O-acetyluridine
CAS Number: 4105-38-8
Molecular Formula: C₁₅H₁₈N₂O₉
Molecular Weight: 370.311
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-09-16 10:49:26
Modify Date: 2024-01-02 11:10:20
Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2].

Name	2',3',5'-Tri-O-acetyluridine
Synonyms	2',3',5-TRI-ACETYLURIDINE EINECS 223-881-5 Vistogard Uridine 2',3',5'-triacetate 2',3',5'-Tri-O-acetyl-rU 2’,3’,5’-Triacetyluridine Uridine, 2',3',5'-triacetate 2`,3`,5`-Tracetyluridine TAU 2',3',5'-Tri-O-acety Tri-O-acetyl uridine 2',3',5'-Tri0acetyluridine (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate 2',3',5'-Tri-O-acetyluridine UNII-2WP61F175M 2',3',5'-Triacetyluridine O2',O3',O5'-triacetyl-uridine uridine triacetate Xuriden 2',3',5'-O-triacetyluridine 2`,3`,5`-Triacetyluridine 2',3',5'-trioacetyluridine MFCD00023795 Vistonuridine

Description	Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2].
Related Catalog	Signaling Pathways >> Others >> Others
References	[1]. Ma WW, et al. Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Cancer. 2017 Jan 1;123(2):345-356. [2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8.

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Hazard Codes	Xi
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