uridine triacetate structure
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Common Name | uridine triacetate | ||
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CAS Number | 4105-38-8 | Molecular Weight | 370.311 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C15H18N2O9 | Melting Point | 124-134ºC | |
MSDS | Chinese USA | Flash Point | N/A |
Use of uridine triacetateUridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. |
Name | 2',3',5'-Tri-O-acetyluridine |
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Synonym | More Synonyms |
Description | Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2]. |
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Related Catalog | |
References |
[2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8. |
Density | 1.4±0.1 g/cm3 |
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Melting Point | 124-134ºC |
Molecular Formula | C15H18N2O9 |
Molecular Weight | 370.311 |
Exact Mass | 370.101227 |
PSA | 142.99000 |
LogP | -0.11 |
Index of Refraction | 1.552 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Precursor 7 | |
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DownStream 10 | |
Evaluation of molecularly imprinted polymers using 2',3',5'-tri-O-acyluridines as templates for pyrimidine nucleoside recognition.
Anal. Bioanal. Chem 406(25) , 6275-84, (2014) In this paper, we describe the synthesis and evaluation of molecularly imprinted polymers (MIPs), prepared using 2',3',5'-tri-O-acyluridines as 'dummy' templates, for the selective recognition of urid... |
2',3',5-TRI-ACETYLURIDINE |
EINECS 223-881-5 |
Vistogard |
Uridine 2',3',5'-triacetate |
2',3',5'-Tri-O-acetyl-rU |
2’,3’,5’-Triacetyluridine |
Uridine, 2',3',5'-triacetate |
2`,3`,5`-Tracetyluridine |
TAU |
2',3',5'-Tri-O-acety |
Tri-O-acetyl uridine |
2',3',5'-Tri0acetyluridine |
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
2',3',5'-Tri-O-acetyluridine |
UNII-2WP61F175M |
2',3',5'-Triacetyluridine |
O2',O3',O5'-triacetyl-uridine |
uridine triacetate |
Xuriden |
2',3',5'-O-triacetyluridine |
2`,3`,5`-Triacetyluridine |
2',3',5'-trioacetyluridine |
MFCD00023795 |
Vistonuridine |