![]() 5-Iodouridine structure
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Common Name | 5-Iodouridine | ||
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CAS Number | 1024-99-3 | Molecular Weight | 370.10 | |
Density | 2.3±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C9H11IN2O6 | Melting Point | 205-207ºC (dec.)(lit.) | |
MSDS | Chinese USA | Flash Point | N/A |
Use of 5-Iodouridine5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
Name | 5-Iodouridine |
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Synonym | More Synonyms |
Description | 5-Iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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Related Catalog | |
References |
Density | 2.3±0.1 g/cm3 |
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Melting Point | 205-207ºC (dec.)(lit.) |
Molecular Formula | C9H11IN2O6 |
Molecular Weight | 370.10 |
Exact Mass | 369.966156 |
PSA | 124.78000 |
LogP | -0.43 |
Index of Refraction | 1.748 |
Storage condition | 2-8°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | R36/37/38 |
Safety Phrases | 22-24/25-36/37/39-27-26 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2934999090 |
~92% 5-Iodouridine CAS#:1024-99-3 |
Literature: Kumar; Wiebe; Knaus Canadian Journal of Chemistry, 1994 , vol. 72, # 9 p. 2005 - 2010 |
~94% 5-Iodouridine CAS#:1024-99-3 |
Literature: Asakura, Jun-ichi; Robins, Morris J. Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4928 - 4933 |
~% 5-Iodouridine CAS#:1024-99-3 |
Literature: Journal of Organic Chemistry, , vol. 55, # 16 p. 4928 - 4933 |
~% 5-Iodouridine CAS#:1024-99-3 |
Literature: Angewandte Chemie - International Edition, , vol. 50, # 9 p. 2155 - 2158 |
Precursor 3 | |
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DownStream 10 | |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis.
PLoS ONE 10 , e0128942, (2015) FOXM1, a member of the forkhead box transcription factor family, plays a key role in cell cycling progression by regulating the expression of critical G1/S and G2/M phase transition genes. In vivo stu... |
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Synthesis of uridine phosphoramidite analogs: reagents for site-specific incorporation of photoreactive sites into RNA sequences.
Bioconjug. Chem. 5(6) , 508-12, (1994) The synthesis of three new photoactive RNA phosphoramidites, 5-bromouridine, 5-iodouridine, and O4-triazolouridine, is reported. The 5' OH of bromouridine and iodouridine were protected as dimethoxytr... |
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Phosphine containing oligonucleotides for the development of metallodeoxyribozymes.
Chem. Commun. (Camb.) (15) , 1556-8, (2007) Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium cata... |
5-Iodouridine |
5-Iod-uridin |
5-Iodoruidine |
2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine |
Uridine, 5-iodo- |
5-iodo-uridine |
EINECS 213-833-1 |
5-Jod-uridin |
5-Iodo-D-uridine |
MFCD00006532 |