Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Chelerythrine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Chelerythrine
Price: ￥Inquiry/5mg
Purity: 97.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Chelerythrine
Price: ￥448.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Chelerythrine
Price: $450.0/100mg $700.0/250mg $1300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Chelerythrine
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

34316-15-9

34316-15-9 structure

34316-15-9 structure

Name: Chelerythrine
Chemical Name: chelerythrine
CAS Number: 34316-15-9
Molecular Formula: C₂₁H₁₈ClNO₄
Molecular Weight: 348.371
Catalog: Biochemical Natural product
Create Date: 2018-06-01 08:00:00
Modify Date: 2024-01-02 08:09:18
Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2].

Name	chelerythrine
Synonyms	[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl- 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium Cheleritrine MFCD00060717 Chelerythrine Chelerythrin-Kation Chelerythrin Chelerythrine chloride 1,2-Dimethoxy-12-methyl[1,3]dioxolo[4,5]benzo[1,2-c]phenanthridin-12-ium Broussonpapyrine Chelerythrin chlorid EINECS 251-930-0

Description	Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> TGF-beta/Smad >> PKC
Target	PKC:0.7 μM (IC50)
References	[1]. Herbert JM, et al. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun. 1990 Nov 15;172(3):993-9. [2]. Shi B, et al. Protein kinase C inhibitor chelerythrine attenuates partial unilateral ureteral obstruction induced kidney injury in neonatal rats. Life Sci. 2019 Jan 1;216:85-91.

Melting Point	195-205ºC
Molecular Formula	C₂₁H₁₈ClNO₄
Molecular Weight	348.371
Exact Mass	348.123047
PSA	40.80000
LogP	0.72060
Storage condition	Desiccate at -20°C

Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S36/37
HS Code	2933990090

87264-52-6 structure

87264-52-6

~2%

34316-15-9 structure

34316-15-9

87264-54-8 structure

87264-54-8

Literature: Heterocycles, , vol. 20, # 8 p. 1535 - 1539

Precursor 1
87264-52-6
DownStream 3
21080-31-9 28342-33-8 6880-91-7

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%