374675-18-0

374675-18-0 structure

Name: Kisspeptin-13 (human) trifluoroacetate salt
Chemical Name: h-leu-pro-asn-tyr-asn-trp-asn-ser-phe-gly-leu-arg-phe-nh2
CAS Number: 374675-18-0
Molecular Formula: C₇₈H₁₀₇N₂₁O₁₈
Molecular Weight: 1626.81000
Catalog: Signaling Pathways GPCR/G Protein GNRH Receptor
Create Date: 2018-11-28 14:21:38
Modify Date: 2024-01-02 07:28:52
Kisspeptin 13 is a GPR54 and GnRH receptor activator, an endogenous active isoform. Kisspeptin 13 enhances memory and can be used in Alzheimer's disease research[1].

Name	h-leu-pro-asn-tyr-asn-trp-asn-ser-phe-gly-leu-arg-phe-nh2
Synonyms	leu-pro-asn-tyr-asn-trp-asn-ser-phe-gly-leu-arg-phe-nh2 kisspeptin-13 Kisspeptin-13 (human)

Description	Kisspeptin 13 is a GPR54 and GnRH receptor activator, an endogenous active isoform. Kisspeptin 13 enhances memory and can be used in Alzheimer's disease research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Neurological Disease
In Vivo	Kisspeptin 13 (intracerebroventricular administration; 2 μg/side; once) treatment improves object recognition memory impairment induced by Aβ through activation of GPR54 and GnRH receptor[1]. Animal Model: Male Swiss mice with memory impairment induced by A-beta[1] Dosage: 2 μg/side Administration: Intracerebroventricular administration; 2 μg/side; once Result: Facilitated memory formation and prolonged memory retention through activation of the GPR54 and GnRH receptors, and suppressed memory-impairing effect of Aβ through activation of the GPR54.