Top Suppliers:I want be here


59988-01-1

59988-01-1 structure
59988-01-1 structure
  • Name: NSC 243928
  • Chemical Name: N-[4-(acridin-9-ylamino)-3-methoxyphenyl]ethanesulfonamide,methanesulfonic acid
  • CAS Number: 59988-01-1
  • Molecular Formula: C23H25N3O6S2
  • Molecular Weight: 503.59100
  • Catalog: Research Areas Cancer
  • Create Date: 2018-06-21 15:02:20
  • Modify Date: 2024-01-03 22:13:28
  • NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1].

Name N-[4-(acridin-9-ylamino)-3-methoxyphenyl]ethanesulfonamide,methanesulfonic acid
Synonyms Ethanesulfonamide,N-(4-(9-acridinylamino)-3-methoxyphenyl)-,monomethanesulfonate
Ethanesulfonamide,N-(4-(acridinyl-9-ylamino)-3-methoxyphenyl)-,methanesulfonate
4'-(9-Acridinylamino)-3'-methoxyethanesulfonanilide methanesulfonate
Ethanesulfonamide,monomethanesulfonate
Ethanesulfonanilide,4'-(9-acridinylamino)-3'-methoxy-,methanesulfonate
Description NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1].
Related Catalog
In Vitro NSC243928 mesylate (2 μM, 24 h) 可以诱导 MDA-MB-231 对照细胞死亡,而在 LY6K 敲低细胞中显示细胞活力增加,进而表明 NSC243928 可能通过 LY6K 途径诱导细胞死亡[1]。 NSC243928 mesylate 作用于MDA-MB-231,Hs-578-T,BT-549,OVCAR-8 细胞的 IC50 值分别是 5.683 μM,7.309 μM,7.954 μM 和 4.167 μM[1]。
References

[1]. Senyi Benti, et al.  Small Molecule Binds with Lymphocyte Antigen 6K to Induce Cancer Cell Death. Cancers (Basel). 2020 Feb 22;12(2):509.   

Boiling Point 571.7ºC at 760 mmHg
Molecular Formula C23H25N3O6S2
Molecular Weight 503.59100
Flash Point 299.5ºC
Exact Mass 503.11800
PSA 154.68000
LogP 6.06230