NSC 243928

Modify Date: 2024-01-03 22:13:28

NSC 243928 structure	Common Name	NSC 243928
	CAS Number	59988-01-1	Molecular Weight	503.59100
	Density	N/A	Boiling Point	571.7ºC at 760 mmHg
	Molecular Formula	C₂₃H₂₅N₃O₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	299.5ºC

Use of NSC 243928

NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1].

Name	N-[4-(acridin-9-ylamino)-3-methoxyphenyl]ethanesulfonamide,methanesulfonic acid
Synonym	More Synonyms

Description	NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	NSC243928 mesylate (2 μM, 24 h) 可以诱导 MDA-MB-231 对照细胞死亡，而在 LY6K 敲低细胞中显示细胞活力增加，进而表明 NSC243928 可能通过 LY6K 途径诱导细胞死亡[1]。 NSC243928 mesylate 作用于MDA-MB-231，Hs-578-T，BT-549，OVCAR-8 细胞的 IC50 值分别是 5.683 μM，7.309 μM，7.954 μM 和 4.167 μM[1]。
References	[1]. Senyi Benti, et al. Small Molecule Binds with Lymphocyte Antigen 6K to Induce Cancer Cell Death. Cancers (Basel). 2020 Feb 22;12(2):509.

Boiling Point	571.7ºC at 760 mmHg
Molecular Formula	C₂₃H₂₅N₃O₆S₂
Molecular Weight	503.59100
Flash Point	299.5ºC
Exact Mass	503.11800
PSA	154.68000
LogP	6.06230

Ethanesulfonamide,N-(4-(9-acridinylamino)-3-methoxyphenyl)-,monomethanesulfonate

Ethanesulfonamide,N-(4-(acridinyl-9-ylamino)-3-methoxyphenyl)-,methanesulfonate

4'-(9-Acridinylamino)-3'-methoxyethanesulfonanilide methanesulfonate

Ethanesulfonamide,monomethanesulfonate

Ethanesulfonanilide,4'-(9-acridinylamino)-3'-methoxy-,methanesulfonate

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NSC 243928
Price: Negotiable
Purity: 99.39%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: NSC 243928
Price: $500.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: NSC 243928
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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