Name | Asperglaucide |
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Synonyms |
(2S)-2-[(N-Benzoyl-L-phenylalanyl)amino]-3-phenylpropyl acetate
Benzenepropanamide, N-[(1S)-2-(acetyloxy)-1-(phenylmethyl)ethyl]-α-(benzoylamino)-, (αS)- Asperglaucide |
Description | Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2]. |
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Related Catalog | |
In Vitro | Aurantiamide acetate inhibits cathepsin L (3.4.22.15) and cathepsin B (3.4.22.1) with IC50 of 12 μM and 49 μM, respectiveiy[1]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 716.1±60.0 °C at 760 mmHg |
Molecular Formula | C27H28N2O4 |
Molecular Weight | 444.522 |
Flash Point | 386.9±32.9 °C |
Exact Mass | 444.204895 |
PSA | 84.50000 |
LogP | 4.58 |
Vapour Pressure | 0.0±2.3 mmHg at 25°C |
Index of Refraction | 1.587 |
Hazard Codes | Xi |
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