Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Moroxydine (hydrochloride)
Price:
Purity: 99.8%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Moroxydine HCl
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Moroxydine HCl
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Moroxydine hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

3160-91-6

3160-91-6 structure

Name: Moroxydine (hydrochloride)
Chemical Name: moroxydine hydrochloride
CAS Number: 3160-91-6
Molecular Formula: C₆H₁₄ClN₅O
Molecular Weight: 207.661
Catalog: API Synthetic anti-infective drugs Antiviral drugs
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-01 19:08:49
Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.Target: Influenza VirusMoroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses [1]. Structurally moroxydine is a heterocyclic biguanidine. Moroxydine was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings [2].

Name	moroxydine hydrochloride
Synonyms	Moroxydine (hydrochloride) 4-Morpholinecarboximidoylguanidine Hydrochloride abobhydrochloride Moroxydine hydrochlorid Hydrogen chloride - N-carbamimidoyl-4-morpholinecarboximidamide (1:1:1) N-Carbamimidoyl-4-morpholinecarboximidamide chlorhydrate (1:1) assur Moroxydine hydrochloride 4-Morpholinecarboximidamide, N-(aminoiminomethyl)-, chloride, hydrogen salt (1:1) N-Carbamimidoyl-4-morpholincarboximidamidhydrochlorid(1:1) N1,N1-Anhydrobis(b-hydroxyethyl)biguanide Hydrochloride N,N-oxapentamethylenebiguanide hydrochloride virusmin N-Carbamimidoyl-4-morpholinecarboximidamide hydrochloride virustat N1-morpholinobiguanidine hydrochloride Miejunging N-amidino-4-morpholincarboxamidine*hydrochloride Malinguchlorate Abitilguanide Hydrochloride flumidin 1-Morpholinobiguanide Hydrochloride N-(aminoiminomethyl)-4-morpholinecarboximidamide hydrochloride (1:1) 4-Morpholinecarboximidamide, N- (aminoiminomethyl)-, monohydrochloride morpholinebiguanide monohydrochloride spenitol N-carbamimidoylmorpholine-4-carboximidamide hydrochloride MORPHOLINO-BIUANIDE HYDROCHLORIDE MOROXYDINE HCL Abitylguanide Hydrochloride N-Carbamimidoylmorpholine-4-carboximidamide hydrochloride (1:1) morpholinebiguanidine hydrochloride

Description	Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.Target: Influenza VirusMoroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses [1]. Structurally moroxydine is a heterocyclic biguanidine. Moroxydine was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings [2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. Sheppard, S., Moroxydine: the story of a mislaid antiviral. Acta Derm Venereol Suppl (Stockh), 1994. 183: p. 1-9. [2]. Moore, Malcolm. "China: All children to be given drug tests after schools caught medicating pupils". The Age. Retrieved 2014-03-20.

Boiling Point	327ºC at 760 mmHg
Melting Point	211-214ºC(lit.)
Molecular Formula	C₆H₁₄ClN₅O
Molecular Weight	207.661
Flash Point	151.6ºC
Exact Mass	207.088684
PSA	98.22000
LogP	0.76700

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD9815000

CHEMICAL NAME :: 4-Morpholinecarboxamidine, N-amidino-, monohydrochloride

CAS REGISTRY NUMBER :: 3160-91-6

LAST UPDATED :: 199501

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H13-N5-O.Cl-H

MOLECULAR WEIGHT :: 207.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >6250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 18,196,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 325 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,474,1960

Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-37/39
WGK Germany	3
RTECS	QD9815000
HS Code	2934999090

10024-89-2

127099-85-8

3160-91-6

Literature: European Journal of Medicinal Chemistry, , vol. 28, # 2 p. 149 - 158

110-91-8

127099-85-8

3160-91-6

Literature: Tetrahedron, , vol. 69, # 19 p. 3867 - 3871

Precursor 2
10024-89-2 110-91-8
DownStream 2
2045-25-2 55558-88-8

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3160-91-6	3731-59-7
10303-96-5	1406-14-0
6138-79-0	127228-87-9
143851-98-3	929-73-7
65546-09-0	1135280-78-2
1158522-08-7	637740-18-2
886897-45-6	940364-43-2
134104-43-1	1694760-18-3
131615-57-1	6906-52-1
930439-75-1	1018584-77-4