Name | Riboflavin (B2) |
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Synonyms |
6,7-dimethyl-9-D-ribitylisoalloxazine
riboflavine D-Ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)- Flavin BB Hibon 1-Deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)-D-ribitol D-Ribitol, 1-deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)- Russupteridine Yellow III VITAMIN B2 (-)-Riboflavin Lactoflavin Riboflavin (B2) Beflavin MFCD00005022 BEFLAVINE 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol EINECS 201-507-1 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol riboflavin EINECS 201-507-1 |
Description | Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.Target: OthersRiboflavin (vitamin B2) is the direct precursor of redox enzyme cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are essential for multiple cell physiology [1]. Urinary excretion of riboflavin contributes to one-half of the overall removal of riboflavin from plasma. No sex differences were observed for any of the pharmacokinetic variables (P > 0.05) [2]. Riboflavin, similar to other vitamins of the B complex, presents anti-inflammatory activity but its full characterization has not yet been carried out. Riboflavin (25, 50 or 100 mg/kg, i.p.), administered immediately and 2 h after the injection of carrageenan, induced antiedema and antinociceptive effects. The antinociceptive effect was not inhibited by the pretreatment with cadmium sulfate (1 mg/kg), an inhibitor of flavokinase. Riboflavin (50 or 100 mg/kg, i.p., 0 and 2 h) also inhibited the fever induced by lipopolysaccharide (LPS) in rats. Riboflavin is a safe drug, is approved for clinical use and exacerbates the antinociceptive effect of morphine, may warrant clinical trials to assess its potential in the treatment of different painful or inflammatory conditions [3]. |
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Related Catalog | |
References |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 715.6±70.0 °C at 760 mmHg |
Melting Point | 290 °C (dec.)(lit.) |
Molecular Formula | C17H20N4O6 |
Molecular Weight | 376.364 |
Flash Point | 386.6±35.7 °C |
Exact Mass | 376.138275 |
PSA | 161.56000 |
LogP | -2.01 |
Vapour Pressure | 0.0±2.4 mmHg at 25°C |
Index of Refraction | 1.733 |
Storage condition | 2~8°C |
Water Solubility | 0.07 g/L (20 ºC) |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Symbol |
GHS02, GHS06, GHS08 |
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Signal Word | Danger |
Hazard Statements | H225-H301 + H311 + H331-H370 |
Precautionary Statements | P210-P260-P280-P301 + P310-P311 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
Hazard Codes | F,T |
Risk Phrases | 11-23/24/25-39/23/24/25 |
Safety Phrases | S24/25 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
WGK Germany | 1 |
RTECS | VJ1400000 |
HS Code | 2936230000 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 2936230000 |
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Summary | 2936230000. unmixed vitaming b2 and deratives(whether or not dissolved in solvents). VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:4.0%. General tariff:20.0% |