Name | kalopanaxsaponin A |
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Synonyms |
α-Hederin
(3β)-3-{[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-23-hydroxyolean-12-en-28-oic acid Alpha-hederin glycosidel-e1 Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-, (3β)- UNII:4H15F0GLV2 sapindosidea HELIXIN nepalin2 dipsacobioside Hederoside B koronaroside A hederosidec akebosidestc taurosidee A-HEDERIN SAPINDOSIDE A HEDERIN Hederin, α- alpha-Hederin |
Description | alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation,In vitro: a-hederin is cytotoxic and inhibits proliferation in bothcel lines at rather low concentrations. , a-hederin reduces themitotic activity in treated cels.[1]In vivo: alpha-hederin had preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses. [2] |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 849.6±65.0 °C at 760 mmHg |
Melting Point | 215ºC (dec.) |
Molecular Formula | C41H66O12 |
Molecular Weight | 750.956 |
Flash Point | 250.7±27.8 °C |
Exact Mass | 750.455444 |
PSA | 195.60000 |
LogP | 8.37 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.601 |
Storage condition | 2~8℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Hazard Codes | Xi |
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Risk Phrases | 22 |
Safety Phrases | 22-45-24/25 |
RIDADR | UN 1544 |
RTECS | RK0177800 |
Precursor 8 | |
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DownStream 4 | |