RN 1747
Modify Date: 2024-01-02 17:44:13
RN 1747 structure
|
Common Name | RN 1747 | ||
|---|---|---|---|---|
| CAS Number | 1024448-59-6 | Molecular Weight | 395.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H18ClN3O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of RN 1747RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1]. |
| Name | 1-benzyl-4-(4-chloro-2-nitrophenyl)sulfonylpiperazine |
|---|---|
| Synonym | More Synonyms |
| Description | RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 0.77 μM (hTRPV4), 4.0 μM (mTRPV4), 4.1 μM (rTRPV4) [1]. |
| References |
| Molecular Formula | C17H18ClN3O4S |
|---|---|
| Molecular Weight | 395.86 |
| Exact Mass | 395.07100 |
| PSA | 94.82000 |
| LogP | 4.23450 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933599090 |
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| RN-1747 |
| 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine |
| 4-CHLORO-2-NITRO-1-((4-BENZYLPIPERAZINYL)SULFONYL)BENZENE |
| 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine |