AF 102A hydrochloride
Modify Date: 2024-01-13 18:12:07
AF 102A hydrochloride structure
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Common Name | AF 102A hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 107220-29-1 | Molecular Weight | 235.77400 | |
| Density | N/A | Boiling Point | 308.5ºC at 760mmHg | |
| Molecular Formula | C10H18ClNOS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 140.4ºC | |
Use of AF 102A hydrochlorideTrans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1]. |
| Name | (2R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane],hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1]. |
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| Related Catalog | |
| Target |
M1[1] |
| In Vivo | AF102A (1 mg/kg; i.p.) reverses cognitive impairments in a step-through passive avoidance task[1]. Animal Model: Rats[1] Dosage: 1 mg/kg Administration: I.p. Result: Reversed cognitive impairments in a step-through passive avoidance task. |
| References |
| Boiling Point | 308.5ºC at 760mmHg |
|---|---|
| Molecular Formula | C10H18ClNOS |
| Molecular Weight | 235.77400 |
| Flash Point | 140.4ºC |
| Exact Mass | 235.08000 |
| PSA | 37.77000 |
| LogP | 2.30010 |
| Vapour Pressure | 0.000676mmHg at 25°C |
| AF 102A HCl |
| trans-Cevimeline Hydrochloride |
| AF 102A hydrochloride |