![]() PF-152 structure
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Common Name | PF-152 | ||
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CAS Number | 1112169-64-8 | Molecular Weight | 473.45800 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H24FN7O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of PF-152PF-152 is a potent, highly selective and orally bioavailable MMP13 inhibitor with Ki of 1.5 nM, with no activity against MMP3 (Ki>10 uM). |
Name | N-(4-Fluoro-3-methoxybenzyl)-6-(2-{[(2S,5R)-5-(hydroxymethyl)-1,4 -dioxan-2-yl]methyl}-2H-tetrazol-5-yl)-2-methyl-4-pyrimidinecarbo xamide |
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Synonym | More Synonyms |
Molecular Formula | C21H24FN7O5 |
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Molecular Weight | 473.45800 |
Exact Mass | 473.18200 |
PSA | 146.40000 |
LogP | 0.68340 |
~25% PF-152 CAS#:1112169-64-8 |
Literature: PFIZER INC. Patent: WO2009/16498 A1, 2009 ; Location in patent: Page/Page column 152-153 ; WO 2009/016498 A1 |
Precursor 2 | |
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DownStream 0 |
PF-152 |