Pyrithione

Modify Date: 2024-01-06 12:32:36

Pyrithione Structure
Pyrithione structure
Common Name Pyrithione
CAS Number 1121-30-8 Molecular Weight 127.16400
Density 1.43g/cm3 Boiling Point 253.8ºC at 760mmHg
Molecular Formula C5H5NOS Melting Point N/A
MSDS N/A Flash Point 107.3ºC

 Use of Pyrithione


Pyrithione is a compound with antibacterial and antifungal activity[1].

 Names

Name pyrithione
Synonym More Synonyms

 Pyrithione Biological Activity

Description Pyrithione is a compound with antibacterial and antifungal activity[1].
Related Catalog
References

[1]. PANSY FE, et al. In vitro studies with 1-hydroxy-2(1H) pyridinethione. Proc Soc Exp Biol Med. 1953 Jan;82(1):122-4.

 Chemical & Physical Properties

Density 1.43g/cm3
Boiling Point 253.8ºC at 760mmHg
Molecular Formula C5H5NOS
Molecular Weight 127.16400
Flash Point 107.3ºC
Exact Mass 127.00900
PSA 57.25000
LogP 1.45490
Vapour Pressure 0.00275mmHg at 25°C
Index of Refraction 1.732
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT9625000
CHEMICAL NAME :
2-(1H)-Pyridinethione, 1-hydroxy-
CAS REGISTRY NUMBER :
1121-30-8
BEILSTEIN REFERENCE NO. :
0109936
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C5-H5-N-O-S
MOLECULAR WEIGHT :
127.17
WISWESSER LINE NOTATION :
T6NYJ AQ BUS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
535 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
108 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOANDB Toxicology Annual. (New York, NY) 1974/75-79. Discontinued. Volume(issue)/page/year: 3,1,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

 Safety Information

HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-hydroxy-2-pyridinethione
2-PYRIDINETHIONE,1-HYDROXY
N-HYDROXYPYRIDINE-2-THIONE
PTO
1-hydroxypyridine-2-thione
N-hydroxy-2-pyridinethione
EINECS 214-328-9
1-hydroxyl-1H-pyridine-2-thione
SQ-2113
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