Ganoderic acid TN

Modify Date: 2024-01-22 20:04:52

Ganoderic acid TN Structure
Ganoderic acid TN structure
Common Name Ganoderic acid TN
CAS Number 112430-64-5 Molecular Weight 512.721
Density 1.1±0.1 g/cm3 Boiling Point 625.5±55.0 °C at 760 mmHg
Molecular Formula C32H48O5 Melting Point N/A
MSDS N/A Flash Point 193.1±25.0 °C

 Use of Ganoderic acid TN


Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].

 Names

Name Ganoderic acid TN
Synonym More Synonyms

 Ganoderic acid TN Biological Activity

Description Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].
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References

[1]. Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 625.5±55.0 °C at 760 mmHg
Molecular Formula C32H48O5
Molecular Weight 512.721
Flash Point 193.1±25.0 °C
Exact Mass 512.350159
LogP 7.87
Vapour Pressure 0.0±4.1 mmHg at 25°C
Index of Refraction 1.555

 Synonyms

(3β,15α,24E)-15-Acetoxy-3-hydroxylanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-
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