112430-64-5

112430-64-5 structure

Name: Ganoderic acid TN
Chemical Name: Ganoderic acid TN
CAS Number: 112430-64-5
Molecular Formula: C₃₂H₄₈O₅
Molecular Weight: 512.721
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2018-11-01 21:10:52
Modify Date: 2024-01-22 20:04:52
Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].

Name	Ganoderic acid TN
Synonyms	(3β,15α,24E)-15-Acetoxy-3-hydroxylanosta-7,9(11),24-trien-26-oic acid Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-

Description	Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.