4-O-Methylepisappanol

Modify Date: 2024-01-02 21:00:50

4-O-Methylepisappanol Structure
4-O-Methylepisappanol structure
Common Name 4-O-Methylepisappanol
CAS Number 112529-37-0 Molecular Weight 318.32100
Density N/A Boiling Point N/A
Molecular Formula C17H18O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-O-Methylepisappanol


4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively[1].

 Names

Name (3R,4R)-3,7-dihydroxy-3-(3,4-dihydroxybenzyl)-4-methoxychroman [4-O-methylepisappanol]
Synonym More Synonyms

 4-O-Methylepisappanol Biological Activity

Description 4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively[1].
Related Catalog
References

[1]. Jeong HJ, et, al. Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibition. Biol Pharm Bull. 2012;35(5):786-90.  

 Chemical & Physical Properties

Molecular Formula C17H18O6
Molecular Weight 318.32100
Exact Mass 318.11000
PSA 99.38000
LogP 1.85710

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

4-O-methylepisappanol