Mal-PEG2-oxyamine

Modify Date: 2024-09-29 16:21:51

Mal-PEG2-oxyamine Structure
Mal-PEG2-oxyamine structure
Common Name Mal-PEG2-oxyamine
CAS Number 1146245-73-9 Molecular Weight 244.24
Density N/A Boiling Point N/A
Molecular Formula C10H16N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG2-oxyamine


Mal-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG2-oxyamine

 Mal-PEG2-oxyamine Biological Activity

Description Mal-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C10H16N2O5
Molecular Weight 244.24