Mal-PEG2-VCP-Eribulin

Modify Date: 2024-01-04 16:00:46

Mal-PEG2-VCP-Eribulin Structure
Mal-PEG2-VCP-Eribulin structure
Common Name Mal-PEG2-VCP-Eribulin
CAS Number 2130869-18-8 Molecular Weight 1374.57
Density N/A Boiling Point N/A
Molecular Formula C70H99N7O21 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG2-VCP-Eribulin


Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].

 Names

Name Mal-PEG2-VCP-Eribulin

 Mal-PEG2-VCP-Eribulin Biological Activity

Description Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].
Related Catalog
References

[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.

[2]. Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505.

 Chemical & Physical Properties

Molecular Formula C70H99N7O21
Molecular Weight 1374.57
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