Xanthopterin

Modify Date: 2024-01-10 22:00:33

Xanthopterin structure	Common Name	Xanthopterin
	CAS Number	119-44-8	Molecular Weight	179.136
	Density	2.2±0.1 g/cm3	Boiling Point	686.5ºC at 760mmHg
	Molecular Formula	C₆H₅N₅O₂	Melting Point	410ºC
	MSDS	N/A	Flash Point	369ºC

Use of Xanthopterin

Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat[1].Xanthopterin inhibits RNA synthesis[4].

Name	xanthopterin
Synonym	More Synonyms

Description	Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat[1].Xanthopterin inhibits RNA synthesis[4].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
In Vitro	Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC50=109 mM)[2]. Cell Viability Assay[2] Cell Line: MCF-7 cells Concentration: 7.8 mM-250 mM Incubation Time: 24 hours Result: Resulted in reduction in mitochondrial activity.
References	[1]. Xanthopterin (XPT), an unconjugated pteridine compound, affects cell growth and differentiation. When injected into rats, XPT has caused changes that have been interpreted as renal growth and hypertrophy. [2]. Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer Lett. 2005 May 10;222(1):119-24. [3]. Plotkin M, et al. Xanthopterin in the Oriental hornet (Vespa orientalis): light absorbance is increased with maturation of yellow pigment granules. Photochem Photobiol. 2009 Jul-Aug;85(4):955-61. [4]. Ziegler I, et al. Pterins and the regulation of lymphocyte activation on the mode of xanthopterin action. Hoppe Seylers Z Physiol Chem. 1984 Jun;365(6):667-73.

Density	2.2±0.1 g/cm3
Boiling Point	686.5ºC at 760mmHg
Melting Point	410ºC
Molecular Formula	C₆H₅N₅O₂
Molecular Weight	179.136
Flash Point	369ºC
Exact Mass	179.044327
PSA	117.52000
LogP	-3.90
Index of Refraction	1.992
Storage condition	2-8°C

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-37/39
HS Code	2933990090

2-amino-6-chlor...

CAS#:146196-27-2

~82%

Xanthopterin

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Literature: Mohr; Kazimierczuk; Pfleiderer Helvetica Chimica Acta, 1992 , vol. 75, # 7 p. 2317 - 2326

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4,6,7(1H)-Pteri...

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Xanthopterin

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Xanthopterin

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Xanthopterin

CAS#:119-44-8

Literature: Helvetica Chimica Acta, , vol. 75, # 7 p. 2317 - 2326

Precursor 5
CAS#:146196-27-2 2-amino-6-chlor... CAS#:1131-35-7 4,6-Pteridinedi... CAS#:492-11-5 4,6,7(1H)-Pteri... CAS#:49653-17-0 Ethyl ethoxyhyd...
CAS#:2757-91-7 2-amino-4,6-dio...
DownStream 4
CAS#:492-11-5 4,6,7(1H)-Pteri... CAS#:645-93-2 Cyanuramide CAS#:56-40-6 Glycine CAS#:6538-79-0 pterorhodin

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-aminopteridine-4(3H),6(5H)-dione

4,6-Pteridinedione,2-amino-1,5-dihydro-(9CI)

4,6-pteridinediol, 2-amino-

Xanthopterin

2-amino-3,5-dihydro-pteridine-4,6-dione

2-amino-1,5-dihydropteridine-4,6-quinone

Uropterin

2-amino-3,5-dihydropteridine-4,6-dione

4,6-Pteridinedione, 2-amino-1,5-dihydro-

6(2H)-Pteridinone, 1,5-dihydro-4-hydroxy-2-imino-

2-AMINO-1,5-DIHYDROPTERIDINE-4,6-DIONE

4-Hydroxy-2-imino-1,5-dihydro-6(2H)-pteridinone

EINECS 204-325-0

2-Amino-3,5-dihydro-pteridin-4,6-dion

4(1H)-pteridinone, 2,3-dihydro-6-hydroxy-2-imino-

2-Amino-1,5-dihydro-4,6-pteridinedione

6-Hydroxy-2-imino-2,3-dihydropteridin-4(1H)-one

2-Amino-4-oxo-6-hydroxy-3,4-dihydropteridine

2-Aminopteridine-4,6-diol

2-azanyl-1,5-dihydropteridine-4,6-dione

2-AMINO-4,6-DIHYDROXYPTERIDENE

2-Amino-4,6(1H,5H)-pteridinedione

MFCD00151242

xanthopterine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Xanthopterin
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Xanthopterin
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4,6-Pteridinedione,2-amino-3,5-dihydro-
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Taiwan Oyi peptide Co. Ltd
China
Product Name: Yeast Extract
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
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