Biotin-PEG1-azide

Modify Date: 2024-01-17 07:50:54

Biotin-PEG1-azide Structure
Biotin-PEG1-azide structure
Common Name Biotin-PEG1-azide
CAS Number 1204085-48-2 Molecular Weight 356.44400
Density N/A Boiling Point N/A
Molecular Formula C14H24N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG1-azide


Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name N-[2-(2-Azidoethoxy)ethyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide

 Biotin-PEG1-azide Biological Activity

Description Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C14H24N6O3S
Molecular Weight 356.44400
Exact Mass 356.16300
PSA 154.51000
LogP 1.65656
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