NH-bis(PEG1-azide)

Modify Date: 2024-01-09 17:01:55

NH-bis(PEG1-azide) Structure
NH-bis(PEG1-azide) structure
Common Name NH-bis(PEG1-azide)
CAS Number 2100306-81-6 Molecular Weight 243.27
Density N/A Boiling Point N/A
Molecular Formula C8H17N7O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH-bis(PEG1-azide)


NH-bis(C2-PEG1-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH-bis(C2-PEG1-azide)

 NH-bis(PEG1-azide) Biological Activity

Description NH-bis(C2-PEG1-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H17N7O2
Molecular Weight 243.27