2100306-83-8

2100306-83-8 structure
2100306-83-8 structure
  • Name: NH-bis(PEG2-propargyl)
  • Chemical Name: NH-bis(PEG2-propargyl)
  • CAS Number: 2100306-83-8
  • Molecular Formula: C14H23NO4
  • Molecular Weight: 269.34
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:06:35
  • Modify Date: 2024-01-10 19:01:01
  • NH-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(PEG2-propargyl)
Synonyms MFCD30730379
Description NH-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H23NO4
Molecular Weight 269.34