TAMRA-PEG4-Alkyne

Modify Date: 2024-01-09 19:11:33

TAMRA-PEG4-Alkyne Structure
TAMRA-PEG4-Alkyne structure
Common Name TAMRA-PEG4-Alkyne
CAS Number 1225057-68-0 Molecular Weight 643.73
Density N/A Boiling Point N/A
Molecular Formula C36H41N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAMRA-PEG4-Alkyne


TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TAMRA-PEG4-alkyne
Synonym More Synonyms

 TAMRA-PEG4-Alkyne Biological Activity

Description TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C36H41N3O8
Molecular Weight 643.73
Storage condition -20°C

 Synonyms

MFCD28505543