APN-C3-PEG4-alkyne

Modify Date: 2024-01-02 18:37:19

APN-C3-PEG4-alkyne Structure
APN-C3-PEG4-alkyne structure
Common Name APN-C3-PEG4-alkyne
CAS Number 2183440-36-8 Molecular Weight 469.53
Density N/A Boiling Point N/A
Molecular Formula C25H31N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of APN-C3-PEG4-alkyne


APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name APN-C3-PEG4-alkyne

 APN-C3-PEG4-alkyne Biological Activity

Description APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H31N3O6
Molecular Weight 469.53
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