2183440-36-8

2183440-36-8 structure
2183440-36-8 structure
  • Name: APN-C3-PEG4-alkyne
  • Chemical Name: APN-C3-PEG4-alkyne
  • CAS Number: 2183440-36-8
  • Molecular Formula: C25H31N3O6
  • Molecular Weight: 469.53
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:54:18
  • Modify Date: 2024-01-02 18:37:19
  • APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name APN-C3-PEG4-alkyne
Description APN-C3-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H31N3O6
Molecular Weight 469.53