ON-01910

Modify Date: 2024-01-04 12:49:05

ON-01910 Structure
ON-01910 structure
Common Name ON-01910
CAS Number 1225497-78-8 Molecular Weight 473.47
Density N/A Boiling Point N/A
Molecular Formula C21H24NNaO8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ON-01910


Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name Rigosertib
Synonym More Synonyms

 ON-01910 Biological Activity

Description Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
Target

PLK1

In Vitro Rigosertib (ON-01910) sodium 是一种非 ATP 竞争性 PLK1 抑制剂,IC50 为 9 nM,比 Plk2 选择性高 30 倍,对 Plk3 没有抑制活性。
References

[1]. Gumireddy K, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell. 2005 Mar;7(3):275-86.  

 Chemical & Physical Properties

Molecular Formula C21H24NNaO8S
Molecular Weight 473.47
Exact Mass 473.112030
PSA 131.60000
LogP 2.62230
Storage condition -20℃

 Synonyms

Glycine, N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-, sodium salt (1:1)
Sodium {[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate
ON-01910
Estybon
Sodium {[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfo nyl}methyl)phenyl]amino}acetate