BPH-1086
Modify Date: 2024-04-04 04:15:35
BPH-1086 structure
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Common Name | BPH-1086 | ||
|---|---|---|---|---|
| CAS Number | 1226901-43-4 | Molecular Weight | 230.05 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C4H8O7P2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BPH-1086BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome[1][2]. |
| Name | BPH-1086 |
|---|
| Description | BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Target: IspH[1] |
| In Vitro | IspH (LytB) is the last enzyme in the nonmevalonate pathway, IspH domains can be fused to either the ribosomal protein S1 (RPS1), IspH–RPS1 binds to mRNA or forms part of the bacterial ribosome[1][2]. IspH–RPS1 proteins are present in anaerobes found in the human gut and some, such as Clostridium botulinum, C. tetani and Fusobacterium nucleatum, are pathogens[2]. IspH inhibitor will therefore kill bacteria directly, as with other antibiotics, but will also kill persistent bacteria by microptosis[3]. |
| References |
| Molecular Formula | C4H8O7P2 |
|---|---|
| Molecular Weight | 230.05 |