mPEG16-Br

Modify Date: 2024-01-04 16:24:10

mPEG16-Br Structure
mPEG16-Br structure
Common Name mPEG16-Br
CAS Number 1238189-11-1 Molecular Weight 799.78
Density N/A Boiling Point N/A
Molecular Formula C33H67BrO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mPEG16-Br


m-PEG16-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG16-Br

 mPEG16-Br Biological Activity

Description m-PEG16-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C33H67BrO16
Molecular Weight 799.78