Myristoyl-Lys-Arg-Thr-Leu-Arg-OH

Modify Date: 2024-01-02 15:17:40

Myristoyl-Lys-Arg-Thr-Leu-Arg-OH Structure
Myristoyl-Lys-Arg-Thr-Leu-Arg-OH structure
Common Name Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
CAS Number 125678-68-4 Molecular Weight 883.17600
Density 1.26g/cm3 Boiling Point N/A
Molecular Formula C42H82N12O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Myristoyl-Lys-Arg-Thr-Leu-Arg-OH


N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].

 Names

Name (2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonym More Synonyms

 Myristoyl-Lys-Arg-Thr-Leu-Arg-OH Biological Activity

Description N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
Related Catalog
In Vitro N-Myristoyl-Lys-Arg-Thr-Leu-Arg (0-50 μM) inhibits the production and release of IL-2 from cultured Jurkat cells stimulated with TPA plus either PHA or OKT3 mAb[1].

 Chemical & Physical Properties

Density 1.26g/cm3
Molecular Formula C42H82N12O8
Molecular Weight 883.17600
Exact Mass 882.63800
PSA 352.85000
LogP 6.31520
Index of Refraction 1.582

 Synonyms

N-Myristoyl-lysyl-arginyl-threonyl-leucyl-arginine
MYRISTOYL-KRTLR-OH
Mlatla
MYRISTOYL-KRTLR-OH INHIBITOR OF PKC
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
N-Myristyl-lys-arg-thr-leu-arg
N2-(N-(N-(N2-(N2-(1-Oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-L-arginine