Bis-propargyl-PEG2

Modify Date: 2024-01-21 12:22:02

Bis-propargyl-PEG2 structure	Common Name	Bis-propargyl-PEG2
	CAS Number	126422-57-9	Molecular Weight	182.21600
	Density	1.02g/mL	Boiling Point	103 °C/0.8kPa
	Molecular Formula	C₁₀H₁₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bis-propargyl-PEG2

Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].

Name	α,ω-bis(O-propargyl)diethylene glycol
Synonym	More Synonyms

Description	Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	Bis-propargyl-PEG2 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].
References	[1]. Shenoi RA, et al. Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators. Biomacromolecules. 2012 Oct 8;13(10):3018-30. [2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

Density	1.02g/mL
Boiling Point	103 °C/0.8kPa
Molecular Formula	C₁₀H₁₄O₃
Molecular Weight	182.21600
Exact Mass	182.09400
PSA	27.69000
LogP	0.30260

3-[2-(2-prop-2-ynyloxyethoxy)ethoxy]propyne

bis-O-propargyl-di(ethylene glycol)

4,7,10-trioxahexadeca-1,12-diyne

4,7,10-trioxatrideca-1,12-diyne

bis(2-propynoxyethyl)ether

4,7,10-trioxatrideca-1,12-diine

Bis-propargyl-PEG2

Use of Bis-propargyl-PEG2

Names

Bis-propargyl-PEG2 Biological Activity

Chemical & Physical Properties

Synonyms