Bis-propargyl-PEG1

Modify Date: 2024-01-14 18:28:43

Use of Bis-propargyl-PEG1

Bis-propargyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	ethylene glycol dipropargyl ether
Synonym	More Synonyms

Description	Bis-propargyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

1-2 bis 2 propynyloxy ethane

1,2-bis(propargyloxy)ethane

1,2-di(2-propynyloxy)ethane

1,2-di-propargyloxyethane

1,2-dipropargyloxyethane

1,2-bis-prop-2-ynyloxy-ethane

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