Sar- [D-Phe8] -des-Arg9-Bradykinin

Modify Date: 2024-04-02 22:24:34

Sar- [D-Phe8] -des-Arg9-Bradykinin Structure
Sar- [D-Phe8] -des-Arg9-Bradykinin structure
Common Name Sar- [D-Phe8] -des-Arg9-Bradykinin
CAS Number 126959-88-4 Molecular Weight 975.10
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C47H66N12O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sar- [D-Phe8] -des-Arg9-Bradykinin


Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].

 Names

Name [Sar,D-Phe8,des-Arg9]bradykinin
Synonym More Synonyms

 Sar- [D-Phe8] -des-Arg9-Bradykinin Biological Activity

Description Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].
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References

[1]. Levesque L, et al. Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta. Br J Pharmacol. 1995 Sep;116(1):1673-9.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C47H66N12O11
Molecular Weight 975.10
Exact Mass 974.497375
LogP 0.44
Index of Refraction 1.677

 Synonyms

[Sar,D-Phe8,des-Arg9]bradykinin
D-Phenylalanine, N-methylglycyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-
N-Methylglycyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-D-phenylalanine
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