[Des-Arg9]-Bradykinin acetate

Modify Date: 2024-01-09 13:10:41

[Des-Arg9]-Bradykinin acetate Structure
[Des-Arg9]-Bradykinin acetate structure
Common Name [Des-Arg9]-Bradykinin acetate
CAS Number 23827-91-0 Molecular Weight 964.07
Density N/A Boiling Point N/A
Molecular Formula C46H65N11O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of [Des-Arg9]-Bradykinin acetate


[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.

 Names

Name [Des-Arg9]-Bradykinin acetate

 [Des-Arg9]-Bradykinin acetate Biological Activity

Description [Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.
Related Catalog
Target

Bradykinin B1 receptor[1]

In Vitro [Des-Arg9]-Bradykinin acetate is a Bradykinin(B1) receptor agonist. The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].
References

[1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

 Chemical & Physical Properties

Molecular Formula C46H65N11O12
Molecular Weight 964.07
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