BS3 Crosslinker disodium

Modify Date: 2024-01-14 14:23:36

BS3 Crosslinker disodium Structure
BS3 Crosslinker disodium structure
Common Name BS3 Crosslinker disodium
CAS Number 127634-19-9 Molecular Weight 572.42900
Density N/A Boiling Point N/A
Molecular Formula C16H18N2Na2O14S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BS3 Crosslinker disodium


BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Suberate Bis(sulfosuccinimidyl) Sodium Salt
Synonym More Synonyms

 BS3 Crosslinker disodium Biological Activity

Description BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C16H18N2Na2O14S2
Molecular Weight 572.42900
Exact Mass 571.99900
PSA 258.52000
Storage condition -20°C

 Synonyms

disodium,1-[8-(2,5-dioxo-3-sulfonatopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
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