127634-19-9

127634-19-9 structure

Name: BS3 Crosslinker disodium
Chemical Name: Suberate Bis(sulfosuccinimidyl) Sodium Salt
CAS Number: 127634-19-9
Molecular Formula: C₁₆H₁₈N₂Na₂O₁₄S₂
Molecular Weight: 572.42900
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-02-09 18:45:51
Modify Date: 2024-01-14 14:23:36
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Suberate Bis(sulfosuccinimidyl) Sodium Salt
Synonyms	disodium,1-[8-(2,5-dioxo-3-sulfonatopyrrolidin-1-yl)oxy-8-oxooctanoyl]oxy-2,5-dioxopyrrolidine-3-sulfonate

Description	BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.