LEE011-D6

Modify Date: 2024-01-12 19:11:46

LEE011-D6 Structure
LEE011-D6 structure
Common Name LEE011-D6
CAS Number 1328934-40-2 Molecular Weight 440.57
Density N/A Boiling Point N/A
Molecular Formula C23H24D6N8O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LEE011-D6


Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].

 Names

Name Ribociclib D6

 LEE011-D6 Biological Activity

Description Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].
Related Catalog
References

[1]. VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10.

 Chemical & Physical Properties

Molecular Formula C23H24D6N8O
Molecular Weight 440.57
Top Suppliers:I want be here


Get all suppliers and price by the below link:

LEE011-D6 suppliers

LEE011-D6 price